Description

(S)-Albuterol Hydrochloride CAS NO 50293-91-9 is the single enantiomer form of the widely used bronchodilator, offering targeted therapeutic action with potentially reduced side effects. This high-purity chiral intermediate is critical for the development and manufacturing of enantiomerically pure pharmaceutical formulations. It is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and producers of advanced respiratory medications seeking to leverage the benefits of stereoselective pharmacology.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as the key chiral building block in the production of enantiopure (S)-albuterol (Levalbuterol) API.
• Pharmaceutical R&D: Used in preclinical and clinical studies to investigate the pharmacokinetics, efficacy, and safety profile of the single (S)-enantiomer.
• Respiratory Drug Formulation: Incorporated into inhalers, nebulizer solutions, and tablets for the treatment of asthma, chronic obstructive pulmonary disease (COPD), and bronchospasm.
• Chiral Reference Standard: Employed as a high-purity standard in analytical methods (e.g., HPLC, Chiral CE) for quality control and regulatory testing of levalbuterol products.
• Metabolite Studies: Utilized in research to understand the metabolic pathways and chiral inversion processes of albuterol.

Basic Information

Product Name	(S)-Albuterol Hydrochloride
CAS No.	50293-91-9
Molecular Formula	C13H22ClNO3
Molecular Weight	275.77 g/mol
Synonyms	(S)-Albuterol HCl; (R,R)-Albuterol Hydrochloride; Levalbuterol Hydrochloride; (S)-Salbutamol Hydrochloride; (-)-Albuterol Hydrochloride; (1R,2S)-Albuterol Hydrochloride; (αR)-α-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol Hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Albuterol Hydrochloride is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and enantiomeric excess, aligning with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing results for assay, chiral purity, related substances, residual solvents, and other critical parameters is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.0%
Single Maximum Unknown Impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.