Description

1-(2,4,6-Triisopropylphenylsulfonyl)Imidazole is a specialized sulfonylation reagent and protecting group agent, primarily used in organic synthesis. Its value lies in its ability to act as a highly effective and selective sulfonylating agent for amines and alcohols, facilitating complex molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries engaged in the development of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the sulfonyl protecting group in multi-step synthesis of active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a coupling agent or protecting group for amino acids during solid-phase and solution-phase peptide synthesis.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require sulfonamide or sulfonate ester functionalities.
• Fine Chemical Manufacturing: Facilitates the production of specialty chemicals, dyes, and functional materials requiring selective sulfonylation.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new synthetic pathways in organic chemistry.
• Nucleoside/Nucleotide Chemistry: Can be applied in the modification of nucleosides for potential therapeutic applications.

Basic Information

Product Name	1-(2,4,6-Triisopropylphenylsulfonyl)Imidazole
CAS No.	50257-40-4
Molecular Formula	C18H26N2O2S
Molecular Weight	334.48 g/mol
Synonyms	Trisyl Imidazole; 2,4,6-Triisopropylbenzenesulfonyl Imidazole; Tipso-Imidazole; 1-[(2,4,6-Triisopropylphenyl)sulfonyl]-1H-imidazole; TPS-Imidazole; 1H-Imidazole, 1-[(2,4,6-triisopropylphenyl)sulfonyl]-; TRISYLIMIDAZOLE; 1-(2,4,6-Triisopropyl-benzenesulfonyl)-imidazole
EINECS	Contact for details

Quality Control

Our 1-(2,4,6-Triisopropylphenylsulfonyl)Imidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial-scale synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions, preferably under an inert atmosphere such as nitrogen or argon, to maintain product integrity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.