Description

(-)-Isoproterenol Hydrochloride CAS NO 5984-95-2 is a high-purity, enantiomerically pure form of the classic β-adrenergic receptor agonist. This compound is critical for research and development in pharmacology and medicinal chemistry, serving as a key reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in cardiovascular, respiratory, and autonomic nervous system research.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS) and for method validation in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of advanced β-agonist drugs and related therapeutic agents.
• Biochemical Research: A vital tool for studying β-adrenergic receptor signaling pathways, mechanisms of action, and receptor-ligand interactions in vitro.
• Pharmacological Studies: Employed in preclinical research to investigate bronchodilation, cardiac stimulation, and vasodilation effects.
• Academic & Educational Use: Supplied to universities and teaching hospitals for advanced pharmacology and medicinal chemistry coursework and research projects.
• Formulation Development: Used in the development and testing of novel drug delivery systems, such as inhalers or injectables, targeting respiratory or cardiac conditions.

Basic Information

Product Name	(-)-Isoproterenol Hydrochloride
CAS No.	5984-95-2
Molecular Formula	C11H17NO3 · HCl
Molecular Weight	247.72 g/mol
Synonyms	(-)-Isoprenaline Hydrochloride; L-Isoproterenol Hydrochloride; (R)-(-)-Isoproterenol Hydrochloride; (R)-4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol Hydrochloride; 3,4-Dihydroxy-α-[(isopropylamino)methyl]benzyl Alcohol Hydrochloride; Isuprel Hydrochloride; Aleudrin; Aludrin; Euspiran; Isopropylarterenol Hydrochloride
EINECS	227-800-2

Quality Control

Our (-)-Isoproterenol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, enantiomeric purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.