Description

2,4,6-Trimethylphenylboronic Acid is a versatile organoboron compound, specifically a substituted phenylboronic acid, widely used as a key building block in modern synthetic chemistry. Its primary value lies in its crucial role as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable precursors for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the mesityl (2,4,6-trimethylphenyl) group can impart favorable stability and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Advanced Material Precursor: Employed in the synthesis of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for constructing complex organic molecules and exploring new synthetic methodologies.
• Fine Chemical Manufacturing: Integral to the production of various high-value specialty chemicals and complex aromatic compounds.

Basic Information

Product Name	2,4,6-Trimethylphenylboronic Acid
CAS No.	5980-97-2
Molecular Formula	C9H13BO2
Molecular Weight	164.01 g/mol
Synonyms	Mesitylboronic Acid; (2,4,6-Trimethylphenyl)boronic Acid; B-(2,4,6-Trimethylphenyl)boronic Acid; 2,4,6-Trimethylbenzeneboronic Acid; Boronic acid, B-(2,4,6-trimethylphenyl)-; Mesitylene-1-boronic acid; 5980-97-2
EINECS	227-819-7

Quality Control

Our 2,4,6-Trimethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Melting Point	~250-260°C (dec.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.