Description

Metazocine Hydrochloride Monohydrate is a high-purity pharmaceutical reference standard and active pharmaceutical ingredient (API) intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the study of opioid receptor pharmacology and analgesic pathways. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions engaged in neuropharmacology and pain management research.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of opioid compounds in research and quality control laboratories.
• Medicinal Chemistry Research: Serves as a key intermediate or building block in the synthesis and study of novel analgesic agents targeting opioid receptors.
• Pharmacological Studies: Employed in in vitro and in vivo studies to investigate the binding affinity, efficacy, and structure-activity relationships (SAR) of benzomorphan derivatives.
• Analytical Method Development: Used as a known compound to develop and validate chromatographic (e.g., HPLC, GC) and spectroscopic analytical methods.
• Academic & Institutional Research: A vital reagent for universities and research institutes focusing on neuropharmacology, pain mechanisms, and drug discovery.

Basic Information

Product Name	Metazocine Hydrochloride Monohydrate
CAS No.	5978-91-6
Molecular Formula	C15H21NO · HCl · H2O
Molecular Weight	285.80 g/mol (monohydrate)
Synonyms	Metazocine HCl monohydrate; 1,2,3,4,5,6-Hexahydro-8-hydroxy-3,6,11-trimethyl-2,6-methano-3-benzazocin-8-ol hydrochloride monohydrate; Win 13,097-2; NIH 7958; 2'-Hydroxy-5,9-dimethyl-2-(2-phenylethyl)-6,7-benzomorphan hydrochloride monohydrate; (±)-Metazocine hydrochloride monohydrate
EINECS	Contact for details

Quality Control

Our Metazocine Hydrochloride Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including identification (IR, NMR), purity assay (HPLC), and control of specific impurities to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) providing batch-specific results is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	5.0% - 7.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity: ≤0.5%; Total impurities: ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.