Description

(-)-8-[(S)-2,3-Dihydroxy-3-Methylbutyl]-7-Methoxy-2H-1-Benzopyran-2-One is a high-purity, optically active coumarin derivative that serves as a critical chiral building block and reference standard in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable intermediate for developing pharmaceuticals and bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise molecular scaffolds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for cardiovascular and anti-inflammatory drugs.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories to ensure product purity and identity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to construct complex molecules with high enantiomeric purity.
• Biochemical Research: Investigated for its biological activity and potential interactions with enzymes or receptors in life science studies.
• Fine Chemical Production: Serves as a specialized intermediate for manufacturing high-value agrochemicals, flavors, and fragrances.
• Academic Research: Utilized in university and institutional labs for studying coumarin chemistry, natural product synthesis, and medicinal chemistry.

Basic Information

Product Name	(-)-8-[(S)-2,3-Dihydroxy-3-Methylbutyl]-7-Methoxy-2H-1-Benzopyran-2-One
CAS No.	5875-49-0
Molecular Formula	C₁₆H₂₀O₅
Molecular Weight	292.33 g/mol
Synonyms	(-)-Marmesin; (S)-Marmesin; NSC 407303; 7-Methoxymarmesin; 8-[(2S)-2,3-Dihydroxy-3-methylbutyl]-7-methoxy-2H-chromen-2-one; 8-(2,3-Dihydroxy-3-methylbutyl)-7-methoxycoumarin; 7-Methoxy-8-(2,3-dihydroxy-3-methylbutyl)coumarin
EINECS	Contact for details

Quality Control

Our (-)-8-[(S)-2,3-Dihydroxy-3-Methylbutyl]-7-Methoxy-2H-1-Benzopyran-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and mass spectrometry, to ensure identity, purity, and enantiomeric excess meet stringent specifications. Certificates of Analysis (COA) documenting all test results are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.