Description

[S,(+)]-2-Bromobutane is a high-purity chiral alkyl halide, specifically the (S)-enantiomer of 2-bromobutane. This compound is a critical chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular stereochemistry for developing active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in nucleophilic substitution and coupling reactions to introduce chiral centers with high enantiomeric excess.
• Agrochemical Research: Employed in creating chiral herbicides, fungicides, and pesticides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organometallic catalysts used in homogeneous catalysis.
• Material Science: Utilized in the development of chiral liquid crystals and polymers with specialized optical properties.
• Academic & Process R&D: A valuable reagent for methodological development and scaling stereoselective reactions in laboratory and pilot plant settings.

Basic Information

Product Name	[S,(+)]-2-Bromobutane
CAS No.	5787-32-6
Molecular Formula	C4H9Br
Molecular Weight	137.02 g/mol
Synonyms	(S)-2-Bromobutane; (+)-(S)-2-Bromobutane; (S)-(+)-sec-Butyl bromide; (2S)-2-Bromobutane; sec-Butyl bromide, (S)-; (S)-sec-Butyl bromide; Butane, 2-bromo-, (2S)-; (S)-Butane-2-bromide
EINECS	227-313-8

Quality Control

Our [S,(+)]-2-Bromobutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, enantiomeric excess, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C to maintain stability and enantiomeric purity. Due to its highly volatile nature, ensure containers are properly sealed.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]D20	+23.0° to +25.0° (c=1, neat)
Water Content (KF)	≤ 0.1%
Refractive Index nD20	1.436 - 1.438
Density (20°C)	1.258 - 1.262 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.