Description

(S)-(+)-1,2-Diphenylethanol is a high-purity chiral secondary alcohol and a valuable enantiomerically enriched building block. Its defined stereochemistry makes it a critical intermediate for the synthesis of pharmaceuticals, agrochemicals, and advanced materials where optical purity is paramount. This compound is essential for researchers and manufacturers in fine chemical synthesis, particularly for developing chiral ligands, catalysts, and active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the production of enantiomerically pure drugs, including antihistamines, anti-inflammatory agents, and CNS-active compounds.
• Asymmetric Catalyst and Ligand Precursor: Used in the preparation of chiral phosphines, oxazolines, and other ligands for asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Agrochemical Intermediate: Employed in the synthesis of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Flavor and Fragrance Industry: Serves as a precursor for chiral aroma chemicals where specific stereoisomers define the sensory profile.
• Material Science Research: Utilized in the development of chiral liquid crystals and polymers with unique optical properties.
• Academic and R&D Laboratories: A standard reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(S)-(+)-1,2-Diphenylethanol
CAS No.	5773-56-8
Molecular Formula	C14H14O
Molecular Weight	198.26 g/mol
Synonyms	(S)-(+)-1,2-Diphenylethanol; (S)-1,2-Diphenylethanol; (S)-(+)-Hydrobenzoin; (S)-Hydrobenzoin; (1S)-1,2-Diphenylethanol; (S)-1,2-Diphenyl-1,2-ethanediol (misnomer, refers to diol); L-1,2-Diphenylethanol; (S)-Enantiomer of 1,2-Diphenylethanol
EINECS	227-304-8

Quality Control

Our (S)-(+)-1,2-Diphenylethanol is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing identity, purity, assay, and specific rotation are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are sealed properly after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	+40° to +44° (c=1 in CHCl3)
Melting Point	62 - 66 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.