Description

4',5-Dimethylangelicin is a synthetic derivative of the naturally occurring furocoumarin angelicin, characterized by the addition of methyl groups at the 4' and 5 positions. This structural modification is significant as it can enhance specific photobiological properties and alter its interaction with biological targets, making it a valuable compound for advanced research. It is primarily utilized by researchers and developers in the fields of pharmaceutical development, photochemistry, and life science research for investigating novel therapeutic pathways and photodynamic mechanisms.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel drug candidates, particularly those targeting skin conditions or exploring photochemotherapy applications.
• Photobiology Studies: Used as a model compound to investigate the mechanisms of photosensitization, DNA intercalation, and the effects of ultraviolet (UV) light on biological systems.
• Academic & Industrial R&D: Employed in chemical and biological laboratories for structure-activity relationship (SAR) studies to understand how substitutions on the angelicin core affect its bioactivity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical chemistry, supporting HPLC, LC-MS, and NMR analyses.
• Biochemical Tool Compound: Utilized in enzymatic and receptor-binding assays to probe specific biological pathways and interactions.

Basic Information

Product Name	4',5-Dimethylangelicin
CAS No.	5762-92-5
Molecular Formula	C15H14O4
Molecular Weight	258.27 g/mol
Synonyms	4',5-Dimethylangelicin; 4',5-Dimethyl-2H-furo[2,3-h][1]benzopyran-2-one; 9-Methoxy-4,7-dimethyl-5H-furo[3,2-g][1]benzopyran-5-one; 4',5-Dimethylpsoralen (related class); Angelicin, 4',5-dimethyl-; Light-sensitive furocoumarin derivative
EINECS	Contact for details

Quality Control

Our 4',5-Dimethylangelicin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.