Description

2-Thiophenecarboxylic Acid, 5-Nitro-, Ethyl Ester is a high-purity organic intermediate characterized by its nitro-substituted thiophene core. This compound is valued for its role as a versatile building block in advanced chemical synthesis, enabling the development of complex molecular architectures. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the thiophene moiety for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of conductive polymers, organic semiconductors, and nonlinear optical materials.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the nitro and ester groups provide specific color and stability properties.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-Nitro-, Ethyl Ester
CAS No.	5751-84-8
Molecular Formula	C7H7NO4S
Molecular Weight	201.20 g/mol
Synonyms	Ethyl 5-Nitro-2-thiophenecarboxylate; 5-Nitro-2-thiophenecarboxylic Acid Ethyl Ester; Ethyl 5-Nitrothiophene-2-carboxylate; 2-Carbethoxy-5-nitrothiophene; 5-Nitrothiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 5-nitro-, ethyl ester; Ethyl 5-nitro-2-thienoate
EINECS	227-267-2

Quality Control

Our 2-Thiophenecarboxylic Acid, 5-Nitro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.