Description

Ethyl 5-Bromothiophene-2-Carboxylate is a high-purity brominated thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromine substituent and ester functionality, enabling precise molecular construction for complex target molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and coordination chemistry.
• Chemical Research: A versatile reagent for heterocyclic and cross-coupling chemistry (e.g., Suzuki, Stille reactions) in academic and industrial laboratories.
• Functional Dye and Pigment Production: Acts as an intermediate for creating dyes with specific light-absorption or emission properties.

Basic Information

Product Name	Ethyl 5-Bromothiophene-2-Carboxylate
CAS No.	5751-83-7
Molecular Formula	C7H7BrO2S
Molecular Weight	235.10 g/mol
Synonyms	5-Bromo-2-thiophenecarboxylic acid ethyl ester; Ethyl 5-bromo-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-bromo-, ethyl ester; 5-Bromothiophene-2-carboxylic Acid Ethyl Ester; 5-Bromo-2-thiophenecarboxylic acid ethyl ester; 5751-83-7; Ethyl 5-bromothiophene-2-carboxylate
EINECS	227-268-7

Quality Control

Our Ethyl 5-Bromothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.