Description

Ethyl 5-Chlorothiophene-2-Carboxylate is a versatile and high-purity organic building block, specifically an ester derivative of a chlorinated thiophene. This compound is valued for its role as a key synthetic intermediate in the production of advanced pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene or chlorinated heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the chlorothiophene moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or building block for creating functional polymers and organic electronic materials with tailored properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, such as Suzuki or Stille couplings, to introduce functionalized thiophene units into more complex molecular architectures.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments that require chlorinated thiophene structures.

Basic Information

Product Name	Ethyl 5-Chlorothiophene-2-Carboxylate
CAS No.	5751-82-6
Molecular Formula	C7H7ClO2S
Molecular Weight	190.65 g/mol
Synonyms	5-Chloro-2-thiophenecarboxylic Acid Ethyl Ester; Ethyl 5-Chloro-2-thiophenecarboxylate; 5-Chlorothiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic Acid, 5-Chloro-, Ethyl Ester; Ethyl 5-Chloro-2-thenoate; 5-Chloro-2-thenoic Acid Ethyl Ester; 5751-82-6; NSC 163022
EINECS	227-268-9

Quality Control

Our Ethyl 5-Chlorothiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.