Description

α-Mercaptobenzeneacrylic Acid is a specialized organosulfur compound featuring both a carboxylic acid and a thiol functional group on a benzene ring. This unique bifunctional structure makes it a valuable chemical intermediate for synthesizing more complex molecules in advanced research and manufacturing. It is primarily utilized by the pharmaceutical and fine chemical industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring thioether or disulfide linkages.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce thiol groups into polymer chains, altering material properties.
• Bioconjugation Chemistry: Employed in the development of linkers for antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive thiol moiety.
• Organic Synthesis Reagent: Functions as a versatile reagent in organic synthesis for Michael addition reactions and other thiol-based transformations.
• Research & Development: A critical compound for chemical research in academic and industrial laboratories exploring new synthetic pathways.

Basic Information

Product Name	α-Mercaptobenzeneacrylic Acid
CAS No.	5740-34-1
Molecular Formula	C9H8O2S
Molecular Weight	180.22 g/mol
Synonyms	2-Mercaptocinnamic Acid; (2E)-3-(2-Sulfanylphenyl)prop-2-enoic Acid; 2-Mercapto-trans-cinnamic Acid; α-Mercaptocinnamic Acid; 2-Thiosalicylic Acid Acrylic Derivative; 3-(2-Mercaptophenyl)acrylic Acid; (E)-3-(2-Mercaptophenyl)acrylic Acid
EINECS	227-250-8

Quality Control

Our α-Mercaptobenzeneacrylic Acid is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our industrial and research partners. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen) for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.