Description

Diphenyl-Pyrrolidin-3-Yl-Methanol is a versatile chiral pyrrolidine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a sophisticated building block in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly within the fields of central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Serves as a chiral auxiliary or ligand in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and enzyme functions.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, targeted crop protection agents.

Basic Information

Product Name	Diphenyl-Pyrrolidin-3-Yl-Methanol
CAS No.	5731-19-1
Molecular Formula	C₁₇H₁₉NO
Molecular Weight	253.34 g/mol
Synonyms	3-(Diphenylhydroxymethyl)pyrrolidine; (RS)-3-(Diphenylhydroxymethyl)pyrrolidine; 3-(Hydroxydiphenylmethyl)pyrrolidine; Pyrrolidin-3-yl(diphenyl)methanol; α-Phenyl-α-(pyrrolidin-3-yl)benzenemethanol; 1,1-Diphenyl-3-pyrrolidinemethanol
EINECS	Contact for details

Quality Control

Our Diphenyl-Pyrrolidin-3-Yl-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.