Description

3-(2,5-Dioxopyrrolidin-1-Yl)Propanoic Acid is a versatile heterocyclic carboxylic acid derivative, serving as a critical bifunctional linker in advanced organic synthesis. Its core value lies in its reactive succinimidyl ester precursor functionality, enabling efficient and selective conjugation under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries who require reliable, high-purity building blocks for creating complex molecules, peptide modifications, and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of targeted drug conjugates and prodrugs.
• Bioconjugation Reagent: Used to crosslink biomolecules (e.g., proteins, peptides, antibodies) with other molecules, dyes, or solid supports for diagnostics, therapeutics, and research.
• Polymer Functionalization: Acts as a monomer or modifier to introduce reactive succinimidyl ester groups into polymer chains for creating smart materials, hydrogels, and drug delivery systems.
• Peptide Synthesis: Employed as a coupling agent or for introducing specific functional handles onto peptide sequences during solid-phase or solution-phase synthesis.
• Surface Chemistry: Used to create functionalized surfaces on chips, beads, or medical devices for biosensing, chromatography, and immobilization applications.
• Chemical Biology Probes: Integral in the design and synthesis of activity-based probes and affinity labels for studying enzyme function and protein interactions.

Basic Information

Product Name	3-(2,5-Dioxopyrrolidin-1-Yl)Propanoic Acid
CAS No.	5724-76-5
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	3-(2,5-Dioxo-1-pyrrolidinyl)propanoic Acid; 1-(2-Carboxyethyl)pyrrolidine-2,5-dione; 3-(N-Succinimidyl)propionic Acid; 3-(2,5-Dioxopyrrolidin-1-yl)propanoic Acid; N-(2-Carboxyethyl)succinimide; Succinimidyl propionate precursor; β-(N-Succinimido)propionic Acid; NSC 3349
EINECS	227-250-9

Quality Control

Our 3-(2,5-Dioxopyrrolidin-1-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our commitment to consistent quality and supply chain reliability supports your critical development and production timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.