Description

Guaifylline is a synthetic xanthine derivative with significant pharmaceutical activity. This compound is valued for its role as a key intermediate in the synthesis of advanced therapeutic agents, particularly those targeting respiratory and cardiovascular conditions. It is primarily sought by manufacturers in the pharmaceutical and fine chemical industries for research, development, and production purposes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) for bronchodilators and vasodilators.
• Research & Development: Used in medicinal chemistry research for developing new xanthine-based therapeutics.
• Fine Chemical Synthesis: Serves as a specialized intermediate in multi-step organic synthesis for high-value compounds.
• Respiratory Drug Formulations: Employed in the development of drugs aimed at treating conditions like asthma and chronic obstructive pulmonary disease (COPD).
• Cardiovascular Drug Development: Investigated for potential use in formulations targeting peripheral vascular diseases.

Basic Information

Product Name	Guaifylline
CAS No.	5634-38-8
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	3-(2-Methoxybenzyl)-7H-purine-2,6-dione; 3-(o-Methoxybenzyl)theophylline; Guaithylline; Guaifenesin Theophylline; Guaifyllinum; Guaiphenesin Theophylline; o-Methoxybenzyltheophylline
EINECS	227-074-1

Quality Control

Our Guaifylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.