Description

Etafedrine Hydrochloride CAS NO 5591-29-7 is a synthetic sympathomimetic amine belonging to the phenethylamine class, widely recognized for its pharmacological activity. This compound is crucial for its role as a key intermediate in the synthesis of more complex active pharmaceutical ingredients (APIs) and for research into adrenergic receptor mechanisms. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of bronchodilators and decongestants.
• Adrenergic Research: Used in biochemical and pharmacological studies to investigate alpha and β-adrenergic receptor activity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Medicinal Chemistry: A valuable starting material for the design and synthesis of novel therapeutic agents targeting the sympathetic nervous system.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of specialized APIs.

Basic Information

Product Name	Etafedrine Hydrochloride
CAS No.	5591-29-7
Molecular Formula	C10H15NO • HCl
Molecular Weight	201.69 g/mol
Synonyms	Etafedrine HCl; N-Ethylnorephedrine Hydrochloride; 2-Amino-1-phenyl-1-propanol, N-ethyl-, hydrochloride; α-[(Ethylamino)methyl]benzenemethanol hydrochloride; Ethylnorephedrine Hydrochloride; Racemic Etafedrine Hydrochloride; (±)-Etafedrine Hydrochloride
EINECS	Contact for details

Quality Control

Our Etafedrine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.