Description

Methyl-D3-Amine CAS NO 5581-55-5 is a deuterium-labeled isotopologue of methylamine, where three hydrogen atoms are replaced by deuterium. This compound is a critical stable isotope-labeled reagent, providing essential internal standards for mass spectrometry and NMR spectroscopy to ensure analytical accuracy and traceability. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced analytical chemistry, drug metabolism studies (DMPK), and the synthesis of labeled compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for quantitative analysis in LC-MS and GC-MS methods, ensuring precise measurement of methylamine and its derivatives in complex matrices.
• NMR Spectroscopy: Serves as a valuable tracer and probe in nuclear magnetic resonance studies for investigating reaction mechanisms and molecular structures.
• Pharmaceutical Research & DMPK: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites within biological systems.
• Synthesis of Deuterated Compounds: Acts as a key building block for the preparation of more complex deuterium-labeled fine chemicals and active pharmaceutical ingredients (APIs).
• Environmental and Food Safety Testing: Enables accurate detection and quantification of methylamine residues in environmental samples and food products.

Basic Information

Product Name	Methyl-D3-Amine
CAS No.	5581-55-5
Molecular Formula	CD3NH2
Molecular Weight	35.08 g/mol
Synonyms	Deuterated Methylamine; Methylamine-d3; (2H3)Methylamine; Methyl-d3-amine; Aminomethane-d3; Monomethylamine-d3; Methanamine-d3; CD3NH2
EINECS	Contact for details

Quality Control

Our Methyl-D3-Amine is produced and handled under stringent quality protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity, and impurity profiles. We adhere to relevant standards for high-purity isotopic chemicals to guarantee reliable and reproducible performance in your research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Due to its gaseous nature and high volatility under standard conditions, this product is typically supplied as a solution or as a gas in a sealed cylinder. Store the container in a cool, well-ventilated area, away from heat sources and incompatible materials. For specific storage and handling instructions related to the supplied form (gas cylinder, ampoule, or solution), please refer to the Safety Data Sheet (SDS).

Specification

Item	Specification
Appearance	Colorless gas / Solution as specified
Identification (IR / NMR)	Conforms
Isotopic Purity (Atom % D)	≥ 98% (or as specified)
Chemical Purity (GC / HPLC)	≥ 99%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.