Description

3-Hydroxythiophene-2,5-Dicarboxylic Acid Dimethyl Ester is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique heterocyclic structure, which provides a versatile platform for constructing complex molecules with tailored electronic and photophysical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to the development of organic semiconductors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its heterocyclic core.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its ester and hydroxyl functional groups.
• Dye and Pigment Research: Acts as a core structure in the synthesis of specialized dyes, pigments, and fluorescent markers.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	3-Hydroxythiophene-2,5-Dicarboxylic Acid Dimethyl Ester
CAS No.	5556-24-1
Molecular Formula	C8H8O5S
Molecular Weight	216.21 g/mol
Synonyms	Dimethyl 3-hydroxythiophene-2,5-dicarboxylate; 2,5-Thiophenedicarboxylic acid, 3-hydroxy-, dimethyl ester; 3-Hydroxy-2,5-thiophenedicarboxylic Acid Dimethyl Ester; Methyl 3-hydroxy-2,5-thiophenedicarboxylate; 3-Hydroxythiophene-2,5-dicarboxylic acid dimethyl ester; 3-Hydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester; 3-Hydroxy-2,5-thiophenedicarboxylic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 3-Hydroxythiophene-2,5-Dicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.