Description

3-Hydroxy-5-Methyl-2-Thiophenecarboxylic Acid Methyl Ester is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for enhanced biological activity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and coordination chemistry.
• Chemical Research: A versatile starting material for heterocyclic and medicinal chemistry research in academic and industrial laboratories.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.

Basic Information

Product Name	3-Hydroxy-5-Methyl-2-Thiophenecarboxylic Acid Methyl Ester
CAS No.	5556-22-9
Molecular Formula	C8H8O3S
Molecular Weight	184.21 g/mol
Synonyms	Methyl 3-hydroxy-5-methylthiophene-2-carboxylate; 5-Methyl-3-hydroxythiophene-2-carboxylic acid methyl ester; 3-Hydroxy-5-methyl-2-thiophenecarboxylic acid, methyl ester; 2-Thiophenecarboxylic acid, 3-hydroxy-5-methyl-, methyl ester; Methyl 3-hydroxy-5-methyl-2-thiophenecarboxylate
EINECS	226-915-6

Quality Control

Our 3-Hydroxy-5-Methyl-2-Thiophenecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical research and advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.