Description

4,5-Di-tert-Butoxy-2-Thiophenecarboxylic Acid Ethyl Ester is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique sterically hindered alkoxy groups, which impart specific electronic and steric properties to target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the thiophene core contributes to biological activity.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: The tert-butoxy groups make it a useful precursor for designing specialized ligands in coordination chemistry and catalysis.
• Chemical Research (R&D): Employed in academic and industrial laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of complex, high-value fine chemicals.

Basic Information

Product Name	4,5-Di-tert-Butoxy-2-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	5556-17-2
Molecular Formula	C17H28O4S
Molecular Weight	328.47 g/mol
Synonyms	Ethyl 4,5-Di-tert-butoxy-2-thiophenecarboxylate; 4,5-Bis(1,1-dimethylethoxy)-2-thiophenecarboxylic Acid Ethyl Ester; 4,5-Di-tert-butoxythiophene-2-carboxylic Acid Ethyl Ester; Ethyl 4,5-Di-tert-butoxythiophene-2-carboxylate; 2-Thiophenecarboxylic Acid, 4,5-Bis(1,1-Dimethylethoxy)-, Ethyl Ester; 4,5-Di-t-Butoxy-2-thiophenecarboxylic Acid Ethyl Ester; DBOT Ethyl Ester
EINECS	Contact for details

Quality Control

Our 4,5-Di-tert-Butoxy-2-Thiophenecarboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.