Description

4-Bromo-3-tert-Butoxythiophene is a high-purity, functionalized thiophene derivative, a key heterocyclic building block in advanced organic synthesis. This compound is valued for its unique reactivity, where the bromine atom serves as an excellent site for cross-coupling reactions, and the tert-butoxy group provides steric bulk and electronic influence. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs), organic electronic materials, and specialty ligands.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that require specific thiophene-based scaffolds for enhanced activity.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: The functional groups make it a valuable starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, exploring new reaction pathways, and creating compound libraries for screening.
• Specialty Fine Chemicals: Incorporated into the synthesis of dyes, pigments, and other performance chemicals where the thiophene moiety imparts desired properties.

Basic Information

Product Name	4-Bromo-3-tert-Butoxythiophene
CAS No.	5556-14-9
Molecular Formula	C8H11BrOS
Molecular Weight	235.14 g/mol
Synonyms	3-tert-Butoxy-4-bromothiophene; 4-Bromo-3-(tert-butoxy)thiophene; 4-Bromo-3-(1,1-dimethylethoxy)thiophene; Thiophene, 4-bromo-3-(1,1-dimethylethoxy)-; 4-Bromo-3-tert-butoxythiophene; 4-Bromo-3-(tert-butyloxy)thiophene; 4-Bromo-3-(tert-butoxy)thiophene; 4-Bromo-3-(t-butoxy)thiophene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-tert-Butoxythiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical: 98.0% - 99.5%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.