Description

2-Acetyl-3-Hydroxythiophene is a versatile heterocyclic building block characterized by its acetyl and hydroxyl substituents on the thiophene ring. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure enables the creation of novel active ingredients. It is primarily needed by research institutions, fine chemical manufacturers, and companies developing advanced materials, flavors, and fragrances.

Application

• Pharmaceutical intermediate for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical precursor in the development of new herbicides, fungicides, and insecticides.
• Key building block for advanced material science, including organic semiconductors and conductive polymers.
• Intermediate in the synthesis of complex flavors and fragrances.
• Research and development (R&D) chemical for academic and industrial laboratories.
• Starting material for the preparation of other functionalized thiophene derivatives.

Basic Information

Product Name	2-Acetyl-3-Hydroxythiophene
CAS No.	5556-07-0
Molecular Formula	C6H6O2S
Molecular Weight	142.18 g/mol
Synonyms	3-Hydroxy-2-acetylthiophene; 1-(3-Hydroxythiophen-2-yl)ethanone; 2-Acetyl-3-thiophenol; 3-Hydroxy-2-thienyl methyl ketone; 2-Thienyl 3-hydroxy methyl ketone; Ethanone, 1-(3-hydroxy-2-thienyl)-; 3-Hydroxy-2-thiophenecarboxaldehyde, acetyl derivative
EINECS	226-904-6

Quality Control

Our 2-Acetyl-3-Hydroxythiophene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.