Description

n-(2-Tosyloxyethyl)Phthalimide is a versatile and high-purity organic synthetic intermediate, primarily used in the construction of complex molecular architectures. This compound is valued for its bifunctional reactivity, featuring both a phthalimide-protected amine and a tosylate leaving group, which facilitates efficient nucleophilic substitution reactions. It is an essential building block for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring ethylenediamine or amino alcohol motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polyimides and other high-performance polymers.
• Organic Synthesis & Research: A valuable reagent for constructing complex organic molecules in academic and industrial R&D laboratories.
• Ligand & Chelator Preparation: Employed in the synthesis of nitrogen-containing ligands for catalysis and metal chelation applications.
• Dye & Pigment Manufacturing: Intermediate in the production of certain colorants and functional dyes.

Basic Information

Product Name	n-(2-Tosyloxyethyl)Phthalimide
CAS No.	5460-83-3
Molecular Formula	C₁₇H₁₅NO₅S
Molecular Weight	345.37 g/mol
Synonyms	2-[(4-Methylphenyl)sulfonyloxy]ethyl-1H-isoindole-1,3(2H)-dione; N-(2-[(Tosyl)oxy]ethyl)phthalimide; 2-(Tosyloxy)ethyl Phthalimide; Phthalimide, N-(2-[(p-tolylsulfonyl)oxy]ethyl)-; 1-(2-Tosyloxyethyl)phthalimide; N-(2-Tosyloxyethyl)phthalimide; N-(2-(p-Toluenesulfonyloxy)ethyl)phthalimide; 5460-83-3
EINECS	226-737-9

Quality Control

Our n-(2-Tosyloxyethyl)Phthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.