Description

3-Cyanoindole is a versatile heterocyclic building block featuring an indole core substituted with a cyano group at the 3-position. This compound is valued for its dual functionality, serving as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers engaged in the synthesis of indole-based alkaloids, active pharmaceutical ingredients (APIs), and advanced materials. Our supply of 3-Cyanoindole CAS NO 5457-28-3 is characterized by high purity and batch-to-batch consistency to support critical R&D and production processes.

Application

• Pharmaceutical Intermediates: A crucial precursor in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its bioactive indole scaffold.
• Material Science Research: Serves as a building block for organic semiconductors, dyes, and photostable polymers.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard for heterocyclic chemistry research.
• Bioconjugation Chemistry: The cyano group can be modified or reduced, enabling its use in linker and probe synthesis for biochemical applications.

Basic Information

Product Name	3-Cyanoindole
CAS No.	5457-28-3
Molecular Formula	C9H6N2
Molecular Weight	142.16 g/mol
Synonyms	Indole-3-carbonitrile; 1H-Indole-3-carbonitrile; 3-Cyanindole; 3-Indolecarbonitrile; 3-CN-Indole; 3-Cyano-1H-indole; β-Cyanoindole
EINECS	226-704-9

Quality Control

Our 3-Cyanoindole is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents. We adhere to cGMP principles where applicable to guarantee reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.