Description

2-Guanidinobenzimidazole is a versatile heterocyclic organic compound featuring a fused benzimidazole core substituted with a guanidino group. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with specific biological or material properties. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting enzymes or receptors where the guanidine and benzimidazole motifs can contribute to binding affinity.
• Agrochemical Synthesis: Used in the creation of new fungicides, herbicides, or plant growth regulators, leveraging its heterocyclic structure for biological activity.
• Coordination Chemistry & Ligand Design: Serves as a precursor for designing chelating ligands in catalysis or for creating metal-organic frameworks (MOFs) due to its multiple nitrogen donor sites.
• Polymer & Material Science: Acts as a monomer or additive for synthesizing specialty polymers, such as polybenzimidazoles, which may exhibit high thermal stability.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or protein-protein interactions.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex heterocyclic dyes and organic pigments.

Basic Information

Product Name	2-Guanidinobenzimidazole
CAS No.	5418-95-1
Molecular Formula	C8H9N5
Molecular Weight	175.19 g/mol
Synonyms	2-Guanidino-1H-benzimidazole; 1H-Benzimidazol-2-ylguanidine; NSC 51128; Guanidine, (1H-benzimidazol-2-yl)-; (1H-Benzimidazol-2-yl)guanidine; 2-(Diaminomethylideneamino)-1H-benzimidazole
EINECS	226-546-7

Quality Control

Our 2-Guanidinobenzimidazole is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.