Description

2-Chloro-4H-1,3,2-Benzodioxaphosphorin-4-One CAS NO 5381-99-7 is a specialized organophosphorus compound featuring a cyclic phosphonate ester structure. This chemical serves as a critical intermediate and reagent in advanced synthetic chemistry, valued for its unique reactivity profile. It is primarily utilized by research institutions and industrial R&D departments focused on developing pharmaceuticals, agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with phosphorus-containing moieties.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and polymerization processes.
• Flame Retardant Research: Investigated as a potential intermediate for developing new generation, halogen-containing organophosphorus flame retardants.
• Material Science: Employed in the creation of specialty polymers and functional materials where the benzodioxaphosphorin ring system imparts specific properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic activity and biological pathways.

Basic Information

Product Name	2-Chloro-4H-1,3,2-Benzodioxaphosphorin-4-One
CAS No.	5381-99-7
Molecular Formula	C7H4ClO3P
Molecular Weight	202.53 g/mol
Synonyms	2-Chloro-2H-1,3,2-benzodioxaphosphorin-2-one; 2-Chloro-1,3,2-benzodioxaphosphole-2-oxide; 2-Chloro-2-oxo-2H-1,3,2-benzodioxaphosphorin; 2-Chloro-2-oxo-1,3,2-benzodioxaphosphorin; 2-Chloro-2-oxo-1,3,2-benzodioxaphosphole; Saligenin cyclic chlorophosphite; Phenyl saligenin phosphorochloridite; NSC 402104
EINECS	226-350-5

Quality Control

Our production of 2-Chloro-4H-1,3,2-Benzodioxaphosphorin-4-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure consistency and reliability for your critical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture ingress, which can lead to decomposition. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.