Description

Meso-1,3-Diphenyl-1,3-Propanediol CAS NO 5381-86-2 is a high-purity, symmetrical diol compound characterized by its meso configuration, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its rigid, symmetrical structure makes it a critical precursor for the preparation of complex ligands, pharmaceuticals, and specialty polymers. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific stereochemistry and functionality into their target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing drugs with specific stereochemical requirements.
• Ligand and Catalyst Synthesis: Used as a backbone for constructing bidentate and polydentate ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Serves as a monomer or chain extender in the production of specialty polyesters and polyurethanes, imparting rigidity and thermal stability.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Building block for fragrances, flavors, and other high-value specialty chemicals requiring precise molecular architecture.
• Academic & Industrial R&D: A standard reagent for methodological studies in organic synthesis, stereochemistry, and catalysis.

Basic Information

Product Name	Meso-1,3-Diphenyl-1,3-Propanediol
CAS No.	5381-86-2
Molecular Formula	C15H16O2
Molecular Weight	228.29 g/mol
Synonyms	meso-Hydrobenzoin; meso-1,3-Diphenyl-1,3-propanediol; 1,3-Diphenyl-1,3-propanediol (meso); (±)-1,3-Diphenyl-1,3-propanediol; DL-1,3-Diphenyl-1,3-propanediol; 1,3-Dihydroxy-1,3-diphenylpropane; NSC 163022
EINECS	226-357-9

Quality Control

Our Meso-1,3-Diphenyl-1,3-Propanediol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	120 - 124 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.