Description

3-Hydroxymethylbenzo[b]thiophene is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a hydroxymethyl group and a benzo[b]thiophene core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. It serves as a key precursor in the development of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiophene moiety.
• Material Science Research: Serves as a monomer or precursor for developing organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes, pigments, and optical brighteners.
• Academic & Industrial R&D: Employed in chemical research for method development, library synthesis, and exploring new chemical reactions.

Basic Information

Product Name	3-Hydroxymethylbenzo[b]thiophene
CAS No.	5381-24-8
Molecular Formula	C9H8OS
Molecular Weight	164.22 g/mol
Synonyms	Benzo[b]thiophen-3-ylmethanol; 3-(Hydroxymethyl)benzo[b]thiophene; 1-Benzothiophen-3-ylmethanol; 3-Hydroxymethyl-1-benzothiophene; 3-Benzo[b]thienylmethanol; 3-Hydroxymethylbenzothiophene; (1-Benzothien-3-yl)methanol
EINECS	Contact for details

Quality Control

Our 3-Hydroxymethylbenzo[b]thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH guidelines, and other relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.