Description

2-Acetyl-5-Bromothiophene is a high-purity brominated thiophene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique molecular structure, featuring both an acetyl and a bromine substituent on the thiophene ring, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, where the thiophene core contributes to biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and organic semiconductors used in OLEDs, solar cells, and field-effect transistors (OFETs).
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new heterocyclic chemistry and reaction methodologies, such as cross-coupling reactions.

Basic Information

Product Name	2-Acetyl-5-Bromothiophene
CAS No.	5370-25-2
Molecular Formula	C6H5BrOS
Molecular Weight	205.07 g/mol
Synonyms	1-(5-Bromo-2-thienyl)ethanone; 5-Bromo-2-acetylthiophene; 5-Bromothiophene-2-yl methyl ketone; 2-Acetyl-5-bromothiophene; 5-Bromo-2-thienyl methyl ketone; 1-(5-Bromothiophen-2-yl)ethan-1-one; Ethanone, 1-(5-bromo-2-thienyl)-
EINECS	226-350-1

Quality Control

Our 2-Acetyl-5-Bromothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.