Description

Dansylamidoethyl Mercaptan is a specialized biochemical reagent featuring a dansyl fluorophore linked to a thiol-reactive moiety. This compound matters for its role as a critical derivatization agent and fluorescent probe in advanced analytical and life science research. It is primarily needed by professionals in pharmaceutical development, proteomics, and analytical chemistry for labeling and detecting thiol-containing biomolecules.

Application

• Derivatization agent for the HPLC and LC-MS analysis of thiols (e.g., cysteine, glutathione).
• Fluorescent labeling of proteins and peptides for detection and quantification studies.
• Research tool in proteomics for studying protein structure, function, and redox states.
• Key intermediate in the synthesis of more complex fluorescent probes and conjugates.
• Use in biochemical assays to monitor enzymatic activity involving thiol groups.
• Development of diagnostic kits and reagents for clinical research applications.

Basic Information

Product Name	Dansylamidoethyl Mercaptan
CAS No.	5354-61-0
Molecular Formula	C14H20N2O2S2
Molecular Weight	312.45 g/mol
Synonyms	5-((2-Mercaptoethyl)amino)naphthalene-1-sulfonamide; Dansylcysteamine; N-(2-Mercaptoethyl)-5-dimethylaminonaphthalene-1-sulfonamide; DNS-Cysteamine; DSAE; Dansylamidoethanethiol; N-Dansyl-2-aminoethanethiol; 1-Dimethylaminonaphthalene-5-sulfonamidoethyl mercaptan
EINECS	226-317-9

Quality Control

Our Dansylamidoethyl Mercaptan is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Solubility Test	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.