Description

Digoxigenin-Mono(Digitoxoside) is a specific, high-purity cardiac glycoside derivative, a key intermediate in the synthesis of digoxin and related compounds. This compound matters for its critical role as a reference standard and a building block in pharmaceutical research and development, ensuring precise biological activity and analytical accuracy. It is primarily needed by pharmaceutical manufacturers, research institutions, and analytical laboratories focused on cardiovascular drug development, biochemical research, and the production of high-purity diagnostic reagents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of the cardiac glycoside drug, Digoxin.
• Reference Standard: Used as a certified reference material (CRM) for quality control and assay validation in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies of Na+/K+-ATPase inhibition and cardiac cell signaling pathways.
• Diagnostic Reagent Production: Serves as a key component in the development of immunoassays and other diagnostic kits.
• Metabolite Studies: Used in research to investigate the metabolism and pharmacokinetics of digoxin and related compounds.
• Academic Research: A valuable tool for universities and research institutes studying steroid chemistry and glycoside biochemistry.

Basic Information

Product Name	Digoxigenin-Mono(Digitoxoside)
CAS No.	5352-63-6
Molecular Formula	C₂₉H₄₄O₉
Molecular Weight	548.66 g/mol
Synonyms	Digoxigenin monodigitoxoside; 3β-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; 12β-Hydroxydigitoxigenin; Digoxigenin-3-O-β-D-digitoxoside; Digoxigenin β-D-digitoxoside; Card-20(22)-enolide, 3-[(2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-, (3β,5β,12β)-
EINECS	226-308-9

Quality Control

Our Digoxigenin-Mono(Digitoxoside) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.