Description

4,5-Dimethyl-Thiazole-2-Thiol is a versatile sulfur and nitrogen-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique thiol-thiazole structure makes it a valuable precursor for pharmaceuticals, agrochemicals, and specialty materials. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and chemical research sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with thiazole cores.
• Agrochemical Synthesis: Building block for developing novel fungicides, herbicides, and insecticides that leverage the bioactivity of the thiazole ring.
• Ligand and Catalyst Preparation: Used to create chelating ligands for metal catalysis in asymmetric synthesis and polymerization processes.
• Material Science: Intermediate in the production of specialty polymers, corrosion inhibitors, and electronic chemicals.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and the discovery of new chemical entities in academic and industrial R&D.
• Flavor & Fragrance Industry: Serves as a precursor for certain sulfur-containing aroma compounds, contributing to savory or roasted notes.

Basic Information

Product Name	4,5-Dimethyl-Thiazole-2-Thiol
CAS No.	5351-51-9
Molecular Formula	C5H7NS2
Molecular Weight	145.25 g/mol
Synonyms	2-Mercapto-4,5-dimethylthiazole; 4,5-Dimethyl-2-mercaptothiazole; 4,5-Dimethyl-1,3-thiazole-2-thiol; 4,5-Dimethyl-2-thiazolethiol; 2-Thiazolethiol, 4,5-dimethyl-; NSC 403697; DTDT
EINECS	226-309-3

Quality Control

Our 4,5-Dimethyl-Thiazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain purity.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	128 - 132 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.