Description

n-(Bromomethyl)Phthalimide is a versatile and highly reactive organic intermediate, primarily valued for its bromomethyl functional group which facilitates efficient alkylation and nucleophilic substitution reactions. This compound is essential for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. It is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce phthalimide-protected amine functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring phthalimide as a protecting group for amines.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its reactive site enables the construction of complex heterocyclic structures.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and functional materials with tailored properties.
• Organic Synthesis Reagent: A valuable reagent for introducing the N-(bromomethyl) moiety in multi-step synthetic routes for fine chemicals and complex organic molecules.
• Ligand & Catalyst Preparation: Employed in the preparation of novel ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Research & Development: A fundamental tool in academic and industrial R&D laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	n-(Bromomethyl)Phthalimide
CAS No.	5332-26-3
Molecular Formula	C9H6BrNO2
Molecular Weight	240.06 g/mol
Synonyms	N-(Bromomethyl)phthalimide; 1H-Isoindole-1,3(2H)-dione, 2-(bromomethyl)-; 2-(Bromomethyl)isoindoline-1,3-dione; Phthalimide, N-(bromomethyl)-; NSC 401122; Bromomethylphthalimide
EINECS	226-228-8

Quality Control

Our n-(Bromomethyl)Phthalimide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.