Description

Hydroxymethyl Triphenylphosphonium Chloride is a versatile organophosphorus reagent, primarily known as a key intermediate in the synthesis of ylides for Wittig olefination reactions. Its value lies in enabling the efficient, stereoselective construction of carbon-carbon double bonds, a fundamental transformation in organic synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity building blocks for complex molecule assembly.

Application

• Wittig Reaction Reagent: Serves as a crucial precursor for generating stabilized ylides used in the synthesis of alkenes, including α,β-unsaturated esters and other functionalized olefins.
• Pharmaceutical Intermediate: Employed in the research and production of active pharmaceutical ingredients (APIs) where specific alkene geometry is critical for biological activity.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides that contain alkene functionalities.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals, flavors, fragrances, and liquid crystal materials.
• Polymer Science: Acts as a monomer or modifying agent in the development of specialized polymers with tailored properties.
• Academic & Industrial R&D: A fundamental tool for methodological development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	Hydroxymethyl Triphenylphosphonium Chloride
CAS No.	5293-83-4
Molecular Formula	C19H18ClOP
Molecular Weight	328.77 g/mol
Synonyms	(Hydroxymethyl)triphenylphosphonium chloride; Triphenylphosphonium methylol chloride; Formylmethylenetriphenylphosphorane chloride precursor; Phosphonium, (hydroxymethyl)triphenyl-, chloride; HTPPC; Wittig reagent precursor
EINECS	226-124-6

Quality Control

Our Hydroxymethyl Triphenylphosphonium Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for water content, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.