Description

(1R,4R)-4,7,7-Trimethylbicyclo[4.1.0]Hept-2-Ene is a high-purity, chiral bicyclic monoterpene derivative that serves as a critical building block in advanced organic synthesis. Its rigid, strained structure and defined stereochemistry make it a valuable intermediate for creating complex molecules with specific spatial orientations. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require precise chiral precursors for the development of active pharmaceutical ingredients (APIs), fragrances, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the production of complex organic molecules, including natural product analogs and specialty chemicals.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing specific terpene-based aroma compounds and odorants.
• Material Science Research: Investigated as a monomer or building block for creating polymers with unique structural properties.
• Catalysis & Ligand Development: Utilized in the development of chiral ligands and catalysts for asymmetric synthesis.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and stereoselective transformations.

Basic Information

Product Name	(1R,4R)-4,7,7-Trimethylbicyclo[4.1.0]Hept-2-Ene
CAS No.	5208-49-1
Molecular Formula	C10H16
Molecular Weight	136.23 g/mol
Synonyms	(1R,4R)-4,7,7-Trimethyl-2-norbornene; (1R,4R)-2-Norcarene; (+)-(1R,4R)-4,7,7-Trimethylbicyclo[4.1.0]hept-2-ene; (1R,4R)-1,4,4-Trimethyl-2,5-cycloheptadiene; 2-Norbornene, 4,7,7-trimethyl-, (1R,4R)-; Chiral 2-Norcarene; d-(+)-4,7,7-Trimethylbicyclo[4.1.0]hept-2-ene
EINECS	Contact for details

Quality Control

Our (1R,4R)-4,7,7-Trimethylbicyclo[4.1.0]Hept-2-Ene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided to guarantee consistency and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.