Description

2-Chloro-4-Formylthiazole is a versatile and highly functionalized heterocyclic building block, essential for advanced organic synthesis. Its core value lies in the reactive aldehyde and chloro substituents, which allow for precise derivatization to create complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiazole-containing drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used to develop advanced fungicides, herbicides, and insecticides where the thiazole ring system imparts specific biological activity.
• Material Science & Organic Electronics: Serves as a building block for creating functional organic molecules used in OLEDs, sensors, and conductive polymers.
• Ligand & Catalyst Development: The formyl group facilitates the creation of novel chelating ligands for metal catalysts used in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new heterocyclic chemistry and reaction methodologies.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments with unique color properties.

Basic Information

Product Name	2-Chloro-4-Formylthiazole
CAS No.	5198-79-8
Molecular Formula	C4H2ClNOS
Molecular Weight	147.58 g/mol
Synonyms	4-Formyl-2-chlorothiazole; 2-Chloro-1,3-thiazole-4-carboxaldehyde; 2-Chlorothiazole-4-carboxaldehyde; Thiazole-4-carboxaldehyde, 2-chloro-; 2-Chloro-4-thiazolecarboxaldehyde; 2-Chloro-4-thiophenecarboxaldehyde (incorrect but common); 4-Aldehyde-2-chlorothiazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Formylthiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.