Description

Benzene, 1,4-Bis(1,1-Dimethylethyl)-2-Iodo- is a high-purity, synthetically valuable iodinated aromatic compound characterized by its sterically hindered tert-butyl groups. This specific molecular architecture makes it a crucial advanced intermediate for the synthesis of complex organic molecules, particularly in pharmaceutical and materials science research. It is primarily sought by R&D chemists and process development scientists working on catalysis, ligand design, and the creation of novel functional materials where precise structural control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring sterically hindered aromatic systems.
• Catalyst & Ligand Precursor: Used in the development of novel organometallic catalysts and specialized ligands for cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive iodine atom and stabilizing tert-butyl groups.
• Advanced Material Synthesis: A foundational monomer for constructing organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs) with tailored electronic and steric properties.
• Agrochemical Research: Employed in the discovery and development of new herbicides, fungicides, or plant growth regulators that incorporate halogenated aromatic motifs.
• Chemical Standard & Reference Material: Used in analytical laboratories as a certified reference standard for method development and quality control in chemical analysis.

Basic Information

Item	Detail
Product Name	Benzene, 1,4-Bis(1,1-Dimethylethyl)-2-Iodo-
CAS No.	5182-66-1
Molecular Formula	C14H21I
Molecular Weight	316.22 g/mol
Synonyms	2-Iodo-1,4-di-tert-butylbenzene; 1,4-Di-tert-butyl-2-iodobenzene; 2-Iodo-p-di-tert-butylbenzene; Di-tert-butyl iodobenzene; 1-Iodo-2,5-di-tert-butylbenzene; Benzene, 2-iodo-1,4-bis(1,1-dimethylethyl)-; 2,5-Di-tert-butyl-1-iodobenzene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1,4-Bis(1,1-Dimethylethyl)-2-Iodo- adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to direct light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.