Description

n-(2-(N,n-Dimethylamino)Ethyl)Maleimide is a specialized bifunctional chemical intermediate featuring both a reactive maleimide group and a tertiary amine. This unique structure makes it a valuable building block for the synthesis of advanced polymers, functional materials, and bioconjugates. It is primarily sought after by researchers and manufacturers in the pharmaceutical, polymer science, and advanced materials sectors for creating tailored molecules with specific properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of drug candidates, particularly for creating antibody-drug conjugates (ADCs) and other targeted therapies via the maleimide-thiol coupling reaction.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce tertiary amine and reactive sites into polymer backbones, enhancing properties like solubility, reactivity, or bioactivity.
• Bioconjugation Reagent: A key reagent for labeling proteins, peptides, and antibodies, enabling the attachment of dyes, drugs, or other functional molecules in life science research.
• Surface Functionalization: Used to modify material surfaces (e.g., nanoparticles, chips) to create reactive interfaces for further chemical grafting or biomolecule immobilization.
• Research & Development: Employed in organic synthesis and chemical biology research to explore new reaction pathways and create novel molecular architectures.

Basic Information

Product Name	n-(2-(N,n-Dimethylamino)Ethyl)Maleimide
CAS No.	5135-58-0
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	N-[2-(Dimethylamino)ethyl]maleimide; 1-[2-(Dimethylamino)ethyl]-1H-pyrrole-2,5-dione; 2,5-Pyrroledione, 1-[2-(dimethylamino)ethyl]-; Maleimide, N-[2-(dimethylamino)ethyl]-; DMAEM; N-(2-Dimethylaminoethyl)maleimide
EINECS	225-879-8

Quality Control

Our n-(2-(N,n-Dimethylamino)Ethyl)Maleimide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.