Description

3-Methoxy-4,5α-Epoxy-7,8-Didehydro-17-Methylmorphinan CAS NO 5121-66-4 is a high-purity, specialized morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of complex opioid-related molecules. It is primarily required by research institutions, pharmaceutical companies, and analytical laboratories engaged in neuropharmacology, medicinal chemistry, and forensic science. Our supply ensures consistent quality and reliable availability for your most demanding R&D and production needs.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel opioid analgesics and antagonists.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical testing laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new therapeutic agents targeting the central nervous system.
• Forensic Analysis: Serves as a critical standard for the identification and quantification of controlled substances and their metabolites.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and biochemical assays.
• Process Development: Acts as a model compound for scaling up synthesis and optimizing manufacturing processes in a GMP environment.

Basic Information

Product Name	3-Methoxy-4,5α-Epoxy-7,8-Didehydro-17-Methylmorphinan
CAS No.	5121-66-4
Molecular Formula	C₁₉H₂₃NO₃
Molecular Weight	313.39 g/mol
Synonyms	3-Methoxy-4,5α-epoxy-7,8-didehydro-17-methylmorphinan; 3-Methoxy-4,5α-epoxy-δ⁷,⁸-17-methylmorphinan; 3-Methoxy-17-methyl-4,5α-epoxymorphinan-7,8-ene; 3-Methoxy-17-methyl-4,5α-epoxy-7,8-didehydromorphinan; 17-Methyl-3-methoxy-4,5α-epoxy-7,8-didehydromorphinan; 3-Methoxy-N-methylmorphinan-4,5α-epoxide-7,8-ene; A key morphinan alkaloid derivative.
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxy-4,5α-Epoxy-7,8-Didehydro-17-Methylmorphinan is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for research and development applications. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available for each lot upon request. Our quality commitment supports compliance with the rigorous standards of the pharmaceutical and analytical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.