Description

3-Hydroxythiophene-2-Carbaldehyde is a versatile heterocyclic building block featuring both aldehyde and hydroxyl functional groups on a thiophene core. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its reactive thiophene scaffold.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for creating metal-organic frameworks (MOFs) and homogeneous catalysts.
• Organic Electronic Materials: A building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Dye and Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments with specific light-absorption properties.
• Chemical Research & Development: A valuable reagent for exploring novel heterocyclic chemistry and creating compound libraries for high-throughput screening.

Basic Information

Product Name	3-Hydroxythiophene-2-Carbaldehyde
CAS No.	5118-08-1
Molecular Formula	C5H4O2S
Molecular Weight	128.15 g/mol
Synonyms	2-Formyl-3-hydroxythiophene; 3-Hydroxy-2-thiophenecarboxaldehyde; 3-Hydroxythiophene-2-carboxaldehyde; 3-Hydroxy-2-thiophenecarbaldehyde; 3-Hydroxythiophene-2-aldehyde; 2-Thiophenecarboxaldehyde, 3-hydroxy-; 3-Hydroxy-2-thiophenealdehyde
EINECS	225-846-7

Quality Control

Our 3-Hydroxythiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.