Description

1,2,3,4-Tetrahydro-6-Methoxy-2-[(4-Methoxyphenyl)Methyl]Isoquinolin-7-Ol is a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, offering precise structural control for research and production. It is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and alkaloid synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tetrahydroisoquinoline-based active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural product analogs and specialty chemicals.
• Alkaloid Synthesis: A fundamental building block for constructing isoquinoline and benzylisoquinoline alkaloid frameworks in laboratory settings.
• Biochemical Tool Compound: Potential use in developing probes for studying enzymatic and receptor-based biological pathways.

Basic Information

Product Name	1,2,3,4-Tetrahydro-6-Methoxy-2-[(4-Methoxyphenyl)Methyl]Isoquinolin-7-Ol
CAS No.	5056-80-4
Molecular Formula	C18H21NO3
Molecular Weight	299.36 g/mol
Synonyms	7-Hydroxy-6-methoxy-2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline; 2-(4-Methoxybenzyl)-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline; 6-Methoxy-7-hydroxy-2-(4-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-hydroxy-6-methoxy-2-(4-methoxybenzyl)isoquinoline; THIQ derivative; Tetrahydroisoquinoline alkaloid intermediate
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-6-Methoxy-2-[(4-Methoxyphenyl)Methyl]Isoquinolin-7-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.