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Bis(Pentafluorophenyl)Hydroxyphosphine CAS NO 5032-93-9


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CAS No.:5032-93-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis(Pentafluorophenyl)Hydroxyphosphine is a specialized organophosphorus compound featuring two highly fluorinated aromatic rings. This structure is critical for its role as a versatile ligand and precursor in advanced catalytic systems and materials science. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing new synthetic methodologies and high-performance materials. Its unique electronic properties, imparted by the pentafluorophenyl groups, make it invaluable for tuning catalyst activity and selectivity.

Application

  • Catalyst Ligand in Cross-Coupling Reactions: Used as a supporting ligand for palladium, nickel, and other transition metals in key reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for complex molecule synthesis.
  • Precursor for Flame Retardants: Serves as a building block for developing novel phosphorus- and fluorine-containing flame retardant additives for polymers and textiles.
  • Intermediate in Pharmaceutical Research: Employed in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly where fluorinated motifs are desired for metabolic stability.
  • Material Science & Polymer Modification: Used to synthesize functional monomers or as an additive to impart specific properties like hydrophobicity or thermal stability to advanced polymers and coatings.
  • Agrochemical Synthesis: Acts as a key intermediate in the production of modern, high-efficacy pesticides and herbicides that require fluorinated organophosphorus structures.
  • Ligand for Olefin Polymerization Catalysts: Investigated as a component in catalyst systems for the polymerization of olefins to create polymers with tailored microstructures.

Basic Information

Product Name Bis(Pentafluorophenyl)Hydroxyphosphine
CAS No. 5032-93-9
Molecular Formula C12H2F10OP
Molecular Weight 380.11 g/mol
Synonyms Hydroxybis(pentafluorophenyl)phosphine; Bis(2,3,4,5,6-pentafluorophenyl)phosphinous acid; (Hydroxy)bis(pentafluorophenyl)phosphine; P,P-Bis(pentafluorophenyl)phosphinous acid; (C6F5)2POH
EINECS Contact for details

Quality Control

Every batch of Bis(Pentafluorophenyl)Hydroxyphosphine is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for research and industrial use. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from strong oxidizers.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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