Description

[2-Chloroethyl(2-Fluoroethyl)Amino]Dichlorophosphine Oxide is a specialized organophosphorus compound of significant interest in advanced chemical synthesis. Its unique structure, featuring both chloroethyl and fluoroethyl amino substituents on a dichlorophosphine oxide core, makes it a valuable precursor for constructing complex phosphorus-containing molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways or requiring specific phosphorus-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides, herbicides, and plant growth regulators where the phosphorus moiety is essential for biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphine ligands used in transition metal catalysis for fine chemical production.
• Flame Retardant Research: Investigated as a potential intermediate for developing high-performance, halogenated organophosphorus flame retardants for polymers and textiles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms, particularly those involving phosphorylation or phosphate transfer.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or chemical resistance properties.

Basic Information

Item	Detail
Product Name	[2-Chloroethyl(2-Fluoroethyl)Amino]Dichlorophosphine Oxide
CAS No.	5001-31-0
Molecular Formula	C4H8Cl3FNOP
Molecular Weight	242.44 g/mol
Synonyms	2-Chloroethyl(2-fluoroethyl)aminodichlorophosphine oxide; N-(2-Chloroethyl)-N-(2-fluoroethyl)phosphoramidic dichloride; Dichloro[N-(2-chloroethyl)-N-(2-fluoroethyl)amino]phosphine oxide; Phosphoramidic dichloride, N-(2-chloroethyl)-N-(2-fluoroethyl)-; (2-Chloroethyl)(2-fluoroethyl)aminophosphonic dichloride
EINECS	Contact for details

Quality Control

Every batch of [2-Chloroethyl(2-Fluoroethyl)Amino]Dichlorophosphine Oxide is produced and tested under a strict quality management system. We ensure high purity and lot-to-lot consistency through comprehensive analytical protocols, including NMR, HPLC, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms to structure
31P NMR	Conforms to structure
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.