Description

1-Aminopropane-2-Thiol (CAS NO 598-36-7) is a versatile organosulfur compound featuring both amine and thiol functional groups, making it a valuable chiral building block and ligand precursor. Its bifunctional nature allows it to act as a key intermediate in the synthesis of complex pharmaceuticals, agrochemicals, and specialty chemicals. This compound is essential for research and production in fine chemical synthesis, pharmaceutical development, and materials science, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its thiol group contributes to biological activity.
• Ligand for Catalysis: Acts as a precursor for chelating ligands in asymmetric catalysis and metal complexation, enhancing reaction selectivity and yield.
• Peptide Modification: Employed in biochemical research for the site-specific modification of peptides and proteins via its reactive thiol moiety.
• Polymer Additive: Functions as a chain transfer agent or cross-linking agent in the production of specialty polymers and resins.
• Flavor & Fragrance Industry: Utilized as an intermediate in the synthesis of sulfur-containing flavor compounds.

Basic Information

Product Name	1-Aminopropane-2-Thiol
CAS No.	598-36-7
Molecular Formula	C3H9NS
Molecular Weight	91.17 g/mol
Synonyms	2-Mercaptopropylamine; 2-Amino-1-propanethiol; 1-Amino-2-mercaptopropane; β-Mercaptoisopropylamine; 2-Aminopropanethiol; Thioisopropanolamine; NSC 8641
EINECS	209-923-2

Quality Control

Our 1-Aminopropane-2-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality. We adhere to relevant ISO and cGMP guidelines where applicable to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent oxidation and degradation. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.