Description

2,-Chloro-4',4''-Bis(Dimethylamino)Trityl Alcohol is a specialized trityl-protected amine derivative, a key intermediate in organic synthesis and pharmaceutical research. Its core value lies in its role as a versatile protecting group for primary amines, enabling selective reactions in complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of nucleoside analogs and other complex drug molecules.
• Oligonucleotide Synthesis: Used as a key reagent in solid-phase synthesis for protecting exocyclic amino groups on nucleobases (e.g., adenine, cytosine, guanine).
• Peptide Chemistry: Serves as a protecting group for amino acids during peptide synthesis, preventing unwanted side reactions.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides as a building block for complex amine-containing structures.
• Material Science: Utilized in the synthesis of functionalized polymers and advanced organic materials requiring protected amine functionalities.
• Academic & R&D: A fundamental reagent in university and industrial research laboratories for methodological development in synthetic organic chemistry.

Basic Information

Item	Details
Product Name	2,-Chloro-4',4''-Bis(Dimethylamino)Trityl Alcohol
CAS No.	596-42-9
Molecular Formula	C23H25ClN2O
Molecular Weight	380.91 g/mol
Synonyms	4,4'-Bis(dimethylamino)trityl chloride, DMT-Cl; Monomethoxytrityl chloride (MMT-Cl) analog; 4-(Dimethylamino)phenylbis[4-(dimethylamino)phenyl]methanol; Chloro-bis(4-dimethylaminophenyl)-p-dimethylaminophenylmethane; p,p'-Bis(dimethylamino)trityl chloride; DMT Chloride; Trityl Chloride Derivative
EINECS	Contact for details

Quality Control

Our 2,-Chloro-4',4''-Bis(Dimethylamino)Trityl Alcohol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and production environments. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical intermediates and advanced synthetic reagents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.