Description

1-Chloro-8-Fluorooctane is a versatile halogenated alkane building block, distinguished by its terminal chloro and fluoro functional groups. This bifunctional structure makes it a valuable intermediate for the synthesis of more complex molecules in advanced chemical manufacturing. It is particularly sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise molecular modifications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated alkyl chains to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of novel herbicides, pesticides, and plant growth regulators where the fluorinated moiety can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing fluorinated components used in display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional side chains into polymers, altering surface properties, hydrophobicity, and chemical resistance.
• Cross-Coupling Reactions: A useful substrate in palladium-catalyzed cross-coupling reactions (e.g., Negishi, Kumada) for carbon-carbon bond formation.
• Surfactant & Fluorosurfactant Research: Investigated for creating novel fluorinated surfactants with unique wetting and spreading characteristics.

Basic Information

Product Name	1-Chloro-8-Fluorooctane
CAS No.	593-14-6
Molecular Formula	C8H16ClF
Molecular Weight	166.66 g/mol
Synonyms	8-Fluoro-1-chlorooctane; Octane, 1-chloro-8-fluoro-; 1-Chlorooctyl fluoride; 8-Fluorooctyl chloride; Fluorooctyl chloride; 1-Fluoro-8-chlorooctane (isomer); ω-Chloro-ω-fluorooctane
EINECS	209-795-7

Quality Control

Our 1-Chloro-8-Fluorooctane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including GC, NMR, and FTIR to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	0.98 - 1.02 g/mL
Refractive Index (n20D)	1.420 - 1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.