Description

1-Bromo-8-Fluorooctane is a versatile bifunctional aliphatic building block featuring both a reactive bromine and a fluorine atom at opposite ends of an eight-carbon chain. This compound matters for its utility in the synthesis of complex molecules, where it serves as a key linker or spacer to introduce fluorinated segments and facilitate further functionalization. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated drug candidates and bioactive molecules, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for creating novel fluorinated pesticides and herbicides, where fluorine enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a fluorinated alkyl chain spacer in the production of advanced display and electronic materials.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, imparting properties like oil repellency, chemical resistance, and low surface energy.
• Cross-Coupling Reactions: The bromine terminus is reactive in palladium-catalyzed couplings (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Surfactant & Fluorosurfactant Research: Used in R&D for synthesizing new fluorinated surfactants with unique surface-active properties.
• Bioconjugation & Probe Development: Functions as a linker for attaching fluorophores or other tags in diagnostic assays and bioconjugation chemistry.
• Organic Synthesis Building Block: A valuable reagent for constructing longer-chain, terminally functionalized organic compounds in medicinal and materials chemistry.

Basic Information

Product Name	1-Bromo-8-Fluorooctane
CAS No.	593-12-4
Molecular Formula	C8H16BrF
Molecular Weight	195.12 g/mol
Synonyms	8-Fluoro-1-bromooctane; Octane, 1-bromo-8-fluoro-; 1-Bromo-8-fluorooctane; 8-Fluorooctyl bromide; Fluorooctyl bromide; (8-Fluorooctyl)bromide; Bromofluorooctane
EINECS	209-800-6

Quality Control

Our 1-Bromo-8-Fluorooctane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and HPLC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.18 g/mL
Refractive Index (n20D)	~1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.