Description

5-Fluoro-1,3-Dihydro-2H-Benzimidazol-2-Thione is a versatile heterocyclic building block and key intermediate in advanced organic synthesis. This compound matters for its role as a privileged scaffold in medicinal chemistry, enabling the development of novel pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents, particularly for applications in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel benzimidazole-based drug candidates with potential anticancer, antiviral, or antimicrobial properties.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators that leverage the benzimidazole-thione core structure.
• Material Science: Acts as a monomer or functional additive in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for constructing complex heterocyclic systems in academic and industrial R&D laboratories.
• Bioconjugation & Probe Development: Utilized in the creation of fluorescent probes, biochemical tags, and diagnostic agents due to its reactive thione group.

Basic Information

Item	Details
Product Name	5-Fluoro-1,3-Dihydro-2H-Benzimidazol-2-Thione
CAS No.	583-42-6
Molecular Formula	C7H5FN2S
Molecular Weight	168.19 g/mol
Synonyms	5-Fluorobenzimidazole-2-thiol; 5-Fluoro-2-mercaptobenzimidazole; 2-Mercapto-5-fluorobenzimidazole; 5-Fluoro-1H-benzimidazole-2-thione; 5-Fluoro-2-benzimidazolethiol; 5-Fluoro-2(3H)-benzimidazolethione; 583-42-6; 5-Fluoro-2-thiobenzimidazolinone
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1,3-Dihydro-2H-Benzimidazol-2-Thione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.