Description

1,2,3,4-Tetrafluorobenzene CAS NO 551-62-2 is a high-purity fluorinated aromatic compound, a key building block in advanced chemical synthesis. Its unique structure, featuring four fluorine atoms on the benzene ring, makes it an essential intermediate for creating complex molecules with tailored properties. This product is critical for R&D and manufacturing in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required to modify reactivity, stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where fluorination improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Imparts heat resistance, chemical stability, and low surface energy properties when incorporated into high-performance polymers and specialty resins.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex fluorinated aromatic systems.
• Research & Development: A valuable standard and starting material in academic and industrial R&D for exploring new fluorination chemistry and material science.

Basic Information

Product Name	1,2,3,4-Tetrafluorobenzene
CAS No.	551-62-2
Molecular Formula	C6H2F4
Molecular Weight	150.07 g/mol
Synonyms	1,2,3,4-Tetrafluorobenzene; Benzene, 1,2,3,4-tetrafluoro-; Tetrafluorobenzene; NSC 9235; Perfluorobenzene (historical, incorrect but used); 1,2,3,4-Tetrafluorobenzol; F4-Benzene (informal); UNII-8F8T8P035U
EINECS	208-996-2

Quality Control

Our 1,2,3,4-Tetrafluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Density (20°C)	~1.5 g/mL
Refractive Index (n20D)	~1.42

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.